PDF （一）目前臺大醫院用於治療攝護腺肥大症之藥品有： 1. tamsulosin （Harnalidge活路利淨口溶錠）以及silodosin ...

Silodosin Uses, Side Effects & Warnings - Drugs.com

Silodosin can affect your pupils. If you need eye surgery, tell the surgeon about your use of silodosin, even if you no longer take it. Silodosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown. Not approved for use by anyone younger than 18 years old.

Silodosin Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD

Silodosin is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH).It does not shrink the prostate, but it works by relaxing the muscles in the prostate and ...

Silodosin (Oral Route) Description and Brand Names - Mayo Clinic

Silodosin is used to treat signs and symptoms of an enlarged prostate gland, which is also known as benign enlargement of the prostate (benign prostatic hyperplasia or BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland gets larger ...

Silodosin - Wikipedia

Silodosin. Silodosin, sold under the brand name Urief among others, is a medication for the symptomatic treatment of benign prostatic hyperplasia. [4] [5] It acts as an alpha-1 adrenergic receptor antagonist. [4] [5] The most common side effect is a reduction in the amount of semen released during ejaculation. [5]

台灣男性學暨性醫學醫學會

Silodosin是較新的選擇性α1-交感神經受體阻斷劑，相較於Tamsulosin，Silodosin有較高的異常射精發生率，它的作用機制在於抑制儲精囊排出精液；然而α1-交感神經受體阻斷劑對於早洩的治療還尚待更多的研究來確定。 【D】PDE-5抑制劑〔PDE-5 inhibitors〕：

Silodosin: Side Effects, Dosage, Uses, and More - Healthline

Silodosin oral capsule is a prescription medication that's used to treat benign prostatic hyperplasia (BPH), or enlarged prostate, in men. It belongs to a class of drugs called alpha-1 blockers.

Silodosin: An Update on Efficacy, Safety and Clinical ... - PubMed

Introduction: Silodosin determines smooth muscle relaxation in bladder and prostate tissues, increases bladder blood flow in conditions of chronic bladder ischemia and regulates the activity of transcriptional factors responsible for stromal growth and prostate hyperplasia. Phase III trials have already demonstrated the efficacy and safety of silodosin in the treatment of patients bothered by ...

Silodosin: MedlinePlus Drug Information

Silodosin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: orgasm with little or no semen (fluid) diarrhea. dizziness. low blood pressure. stuffy or runny nose. Some side effects can be serious. If you experience any of these symptoms , call your doctor immediately:

Evolving Role of Silodosin for the Treatment of Urological Disorders ...

Evolution of Silodosin for Treatment of Urological Disorders. Silodosin, is the most selective antagonist of the α 1A-adrenoreceptors (ARs) family.Silodosin was approved first in Japan in 2006, and later received approval in the USA25 and Europe.26,27 Receptor-binding studies were conducted to study the effect of silodosin and other α 1-AR antagonists on the increase in intraurethral ...

Silodosin Side Effects: Common, Severe, Long Term - Drugs.com

Applies to silodosin: oral capsule. Serious side effects of Silodosin. Along with its needed effects, silodosin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking silodosin:

台灣性功能障礙諮詢暨訓練委員會

Silodosin是較新的選擇性α1-交感神經受體阻斷劑，相較於Tamsulosin，Silodosin有較高的異常射精發生率，它的作用機制在於抑制儲精囊排出精液；然而α1-交感神經受體阻斷劑對於早洩的治療還尚待更多的研究來確定。 【D】PDE-5抑制劑〔PDE-5 inhibitors〕：

Safety and efficacy of silodosin for the treatment of benign prostatic ...

Molecular and pharmacological characteristics of silodosin. A number of α 1-adrenergic receptor antagonists (alfuzosin, doxazosin, tamsulosin, terazosin, naftopidil) have been approved for the treatment of BPH worldwide.The earlier α 1-adrenergic receptor antagonists cause vasodilatory symptoms, including postural hypotension and dizziness, and have to be used carefully in patients ...

Efficacy and safety of silodosin in the treatment of lower urinary ...

Silodosin showed a 56-fold selectivity for the α1A versus α1D subtype and a 583-fold selectivity for the α1A vs. α1B subtype. 10 The relatively low selectivity for the α1B adrenergic receptor, which is mainly involved in the regulation of blood pressure, allows silodosin to have minimal effects on the cardiovascular system. 10, 11, 12 In a ...

Silodosin (Oral Route) Proper Use - Mayo Clinic

Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (capsules): For benign prostatic hyperplasia (BPH): Adults—8 milligrams (mg) once a day. Children—Use is not recommended.

Effects of silodosin on sexual function - realistic picture from the ...

Silodosin confirms to be highly effective in patients with LUTS/BPH; of them, almost 70% report either anejaculation or hypospermia, with a concomitant OF impairment in 17% of the patients. Younger patients showed higher rates of a concomitant impairment of ejaculation and OF. Overall, anejaculation caused drug discontinuation in 7% of the ...

Sandoz Silodosin - Uses, Side Effects, Interactions - MedBroadcast.com

red or purple discolouration of the skin. signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools) Stop taking the medication and seek immediate medical attention if any of the following occur:

Silodosin (Rapaflo): Uses, Side Effects, Alternatives & More - GoodRx

Silodosin (Rapaflo) is used to treat symptoms of benign prostatic hyperplasia (BPH), or having an enlarged prostate. This medication is available as a brand-name and generic version, and it comes as a capsule that you take by mouth. The dosage is typically just once daily with a meal, but it can affect your ejaculation as a side effect (for ...

SILODOSIN的適應症、成分、用法與用量、作用機轉、副作用

回應. SILODOSIN的用量、作用機轉、副作用、懷孕及哺乳用藥與藥物交互作用，SILODOSIN適應症:治療前列腺肥大症所伴隨的排尿障礙。.

Silodosin: Uses, Interactions, Mechanism of Action | DrugBank Online

Generic Name Silodosin DrugBank Accession Number DB06207 Background. Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α 1A subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the α 1A subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. 2

良性攝護腺肥大之藥物治療 作者：臺大醫院藥劑部黃韋龍藥師 專題報導 2013年08月臺大醫院健康電子報

Alpha1受體主要有三種亞型 （1A、1B以及1D），其中以tamsulosin （主要作用於1A、1D）以及silodosin （主要作用於1A）之受體選擇性最高，因此最不容易造成低血壓之副作用；1B亞型常見於血管平滑肌上，因此terazosin與doxazosin亦常使用於高血壓的治療。

Effectiveness of 'on demand' silodosin in the treatment of premature ...

The silodosin-treated group reported an average score of 1.82 ±0.85 (corresponding to much improved), whereas the placebo treated group reported an average score of 3.8 ±0.63 (corresponding to almost no improvement). The scatter diagrams showing the clinical global impression of change for premature ejaculation ...